Absence of modulatory effects of 6Hz cerebellar transcranial alternating current stimulation on fear learning in men.

ABSTRACT: Fear is a vital defense mechanism to potential threats, which is influenced by the cerebellum. While the cerebellum's role in acquiring fear responses is well understood, limited knowledge exists about its involvement in fear extinction. In this study, we investigated the effects of cerebellar theta band transcranial alternating current stimulation (ctACS) administered during fear extinction training, based on previous evidence from animal studies suggesting a role of cerebellar theta oscillations in associative memory formation. To this end, thirty-seven healthy right-handed male participants were recruited for a two-day differential fear renewal paradigm. On day 1, they underwent acquisition training in context A followed by extinction training in context B. On day 2, recall was tested i

SUBMITTER: Schellen SJ 

PROVIDER: S-EPMC10803490 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature