Digital consults to optimize guideline-directed therapy: design of a pragmatic multicenter randomized controlled trial.

ABSTRACT:

Aims

Many heart failure (HF) patients do not receive optimal guideline-directed medical therapy (GDMT) despite clear benefit on morbidity and mortality outcomes. Digital consults (DCs) have the potential to improve efficiency on GDMT optimization to serve the growing HF population. The investigator-initiated ADMINISTER trial was designed as a pragmatic multicenter randomized controlled open-label trial to evaluate efficacy and safety of DC in patients on HF treatment.

Methods and results

Patients (n = 150) diagnosed with HF with a reduced ejection fraction will be randomized to DC or standard care (1:1). The intervention group receives multifaceted DCs including (i) digital data sharing (e.g. exchange of pharmacotherapy use and home-measured vital signs), (ii) patient educat

SUBMITTER: Man JP 

PROVIDER: S-EPMC10804150 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature