Clinical predictors of right ventricular dysfunction and association with adverse outcomes in peripartum cardiomyopathy.

ABSTRACT:

Aims

We sought to identify factors associated with right ventricular (RV) dysfunction and elevated pulmonary artery systolic pressure (PASP) and association with adverse outcomes in peripartum cardiomyopathy (PPCM).

Methods and results

We conducted a multi-centre cohort study to identify subjects with PPCM with the following criteria: left ventricular ejection fraction (LVEF) < 40%, development of heart failure within the last month of pregnancy or 5 months of delivery, and no other identifiable cause of heart failure with reduced ejection fraction. Outcomes included a composite of (i) major adverse events (need for extracorporeal membrane oxygenation, ventricular assist device, orthotopic heart transplantation, or death) or (ii) recurrent heart failure hospitalization. RV f

SUBMITTER: Imran TF 

PROVIDER: S-EPMC10804155 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature