Calcium channel blockers and clinical outcomes in patients with continuous-flow left ventricular assist devices.

ABSTRACT:

Aims

Current guidelines suggest calcium channel blockers (CCBs) as the second or third option for blood pressure management in patients with left ventricular assist device (LVAD). However, the clinical outcomes of patients with LVAD who receive CCBs remain unclear. Our study aims to analyse the association of CCBs with clinical outcomes in patients after LVAD implantation.

Methods and results

This is a retrospective analysis based on the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) from 2006 to 2017, and adult patients who were alive with LVAD and CCB treatment information at 6 months after implantation were included. Among 10 717 patients, 1369 received CCBs 6 months after implantation, and there was an increasing trend of CCB use after LVA

SUBMITTER: Tie H 

PROVIDER: S-EPMC10804166 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature