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StRAB4 gene is required for filamentous growth, conidial development, and pathogenicity in Setosphaeria turcica.


ABSTRACT: Setosphaeria turcica, the fungal pathogen responsible for northern corn leaf blight in maize, forms specialized infectious structures called appressoria that are critical for fungal penetration of maize epidermal cells. The Rab family of proteins play a crucial role in the growth, development, and pathogenesis of many eukaryotic species. Rab4, in particular, is a key regulator of endocytosis and vesicle trafficking, essential for filamentous growth and successful infection by other fungal pathogens. In this study, we silenced StRAB4 in S. turcica to gain a better understanding the function of Rab4 in this plant pathogen. Phenotypically, the mutants exhibited a reduced growth rate, a significant decline in conidia production, and an abnormal conidial morphology. These p

SUBMITTER: Li P 

PROVIDER: S-EPMC10804457 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature