Adipokines in atopic dermatitis: the link between obesity and atopic dermatitis.

ABSTRACT: Atopic dermatitis (AD) is a chronic skin condition with intense pruritus, eczema, and dry skin. The recurrent intense pruritus and numerous complications in patients with AD can profoundly affect their quality of life. Obesity is one of its comorbidities that has been confirmed to be the hazard factor of AD and also worsen its severity. Nevertheless, the specific mechanisms that explain the connection between obesity and AD remain incompletely recognized. Recent studies have built hopes on various adipokines to explain this connection. Adipokines, which are disturbed by an obese state, may lead to immune system imbalances in people with AD and promote the development of the disease. This review focuses on the abnormal expression patterns of adipokines in patients with AD and their potentia

SUBMITTER: Zhang S 

PROVIDER: S-EPMC10804547 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature