Left main coronary artery morphological phenotypes and its hemodynamic properties.

ABSTRACT:

Background

Atherosclerosis may be linked to morphological defects that lead to variances in coronary artery hemodynamics. Few objective strategies exit at present for generalizing morphological phenotypes of coronary arteries in terms of hemodynamics. We used unsupervised clustering (UC) to classify the morphology of the left main coronary artery (LM) and looked at how hemodynamic distribution differed between phenotypes.

Methods

In this study, 76 LMs were obtained from 76 patients. After LMs were reconstructed with coronary computed tomography angiography, centerlines were used to extract the geometric characteristics. Unsupervised clustering was carried out using these characteristics to identify distinct morphological phenotypes of LMs. The time-averaged wall shear stress

SUBMITTER: Wang Q 

PROVIDER: S-EPMC10804578 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature