Blood glucose and lipids are associated with sarcoidosis: findings from observational and mendelian randomization studies.

ABSTRACT:

Background

Several researches have demonstrated that patients with sarcoidosis accompanied with the abnormality in blood glucose and/or lipids, however, the causal relationship between them remains uncertain. To elucidate the potential association and causality of blood glucose and lipids with sarcoidosis, we conducted a propensity score matching (PSM)-based observational study combined with mendelian randomization (MR) analysis.

Methods

All subjects in this study were retrospectively collected from Tongji Hospital during 2010 and 2023. 1:1 PSM was employed to control the potential confounders as appropriate. Univariable and multivariable logistic regression analyses were performed to estimate the associations of sarcoidosis with fasting glucose, high density lipoprotein cho

SUBMITTER: Zhan Y 

PROVIDER: S-EPMC10804582 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature