Clinical outcomes of long-term inhaled combination therapies in patients with bronchiectasis and airflow obstruction.

ABSTRACT:

Background and objectives

Few studies have reported which inhaled combination therapy, either bronchodilators and/or inhaled corticosteroids (ICSs), is beneficial in patients with bronchiectasis and airflow obstruction. Our study compared the efficacy and safety among different inhaled combination therapies in patients with bronchiectasis and airflow obstruction.

Methods

Our retrospective study analyzed the patients with forced expiratory volume in 1 s (FEV₁)/forced vital capacity < 0.7 and radiologically confirmed bronchiectasis in chest computed tomography between January 2005 and December 2021. The eligible patients underwent baseline and follow-up spirometric assessments. The primary endpoint was the development of a moderate-to-severe exacerbation. The second

SUBMITTER: Lee HJ 

PROVIDER: S-EPMC10804611 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature