The benefits and risks of menopause hormone therapy for the cardiovascular system in postmenopausal women: a systematic review and meta-analysis.

ABSTRACT:

Background

Menopause hormone therapy (MHT), as an effective method to alleviate the menopause-related symptoms of women, its benefits, risks, and potential influencing factors for the cardiovascular system of postmenopausal women are not very clear.

Objectives

To evaluate cardiovascular benefits and risks of MHT in postmenopausal women, and analyze the underlying factors that affect both.

Search strategy

The EMBASE, MEDLINE, and CENTRAL databases were searched from 1975 to July 2022.

Selection criteria

Randomized Clinical Trials (RCTs) that met pre-specified inclusion criteria were included.

Data collection and analysis

Two reviewers extracted data independently. A meta-analysis of random effects was used to analyze data.

Main results

This systema

SUBMITTER: Gu Y 

PROVIDER: S-EPMC10804786 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature