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Efficacy of permissive underfeeding for critically ill patients: an updated systematic review and trial sequential meta-analysis.


ABSTRACT:

Background

Our previous study in 2011 concluded that permissive underfeeding may improve outcomes in patients receiving parenteral nutrition therapy. This conclusion was tentative, given the small sample size. We conducted the present systematic review and trial sequential meta-analysis to update the status of permissive underfeeding in patients who were admitted to the intensive care unit (ICU).

Methods

Seven databases were searched: PubMed, Embase, Web of Science, China National Knowledge Infrastructure, Wanfang, Chinese Biomedical Literature Database, and Cochrane Library. Randomized controlled trials (RCTs) were included. The Revised Cochrane risk-of-bias tool (ROB 2) was used to assess the risk of bias in the enrolled trials. RevMan software was used for data synthesis.

SUBMITTER: Yue HY 

PROVIDER: S-EPMC10804832 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature