Influence of dengue virus serotypes on the abundance of <i>Aedes aegypti</i> insect-specific viruses (ISVs).

ABSTRACT: A comprehensive understanding of the virome in mosquito vectors is crucial for assessing the potential transmission of viral agents, designing effective vector control strategies, and advancing our knowledge of insect-specific viruses (ISVs). In this study, we utilized Oxford Nanopore Technologies metagenomics to characterize the virome of Aedes aegypti mosquitoes collected in various regions of Colombia, a country hyperendemic for dengue virus (DENV). Analyses were conducted on groups of insects with previous natural DENV infection (DENV-1 and DENV-2 serotypes), as well as mosquito samples that tested negative for virus infection (DENV-negative). Our findings indicate that the Ae. aegypti virome exhibits a similar viral composition at the ISV family and species levels in bot

SUBMITTER: Gomez M 

PROVIDER: S-EPMC10804971 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature