Transcriptional pathways across colony biofilm models in the symbiont Vibrio fischeri.

ABSTRACT: Beneficial microbial symbionts that are horizontally acquired by their animal hosts undergo a lifestyle transition from free-living in the environment to associating with host tissues. In the model symbiosis between the Hawaiian bobtail squid and its microbial symbiont Vibrio fischeri, one mechanism used to make this transition during host colonization is the formation of biofilm-like aggregates in host mucosa. Previous work identified factors that are sufficient to induce V. fischeri biofilm formation, yet much remains unknown regarding the breadth of target genes induced by these factors. Here, we probed two widely used in vitro models of biofilm formation to identify novel regulatory pathways in the squid symbiont V. fischeri ES114. We discovered a shared set

SUBMITTER: Vander Griend JA 

PROVIDER: S-EPMC10804989 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature