Spatio-temporal coherence of circadian clocks and temporal control of differentiation in Anabaena filaments.

ABSTRACT: Circadian clock arrays in multicellular filaments of the heterocyst-forming cyanobacterium Anabaena sp. strain PCC 7120 display remarkable spatio-temporal coherence under nitrogen-replete conditions. To shed light on the interplay between circadian clocks and the formation of developmental patterns, we followed the expression of a clock-controlled gene under nitrogen deprivation, at the level of individual cells. Our experiments showed that differentiation into heterocysts took place preferentially within a limited interval of the circadian clock cycle, that gene expression in different vegetative intervals along a developed filament was discoordinated, and that the circadian clock was active in individual heterocysts. Furthermore, Anabaena mutants lacking the kaiABC g

SUBMITTER: Arbel-Goren R 

PROVIDER: S-EPMC10805033 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature