Deuteration of heptamethine cyanine dyes enhances their emission efficacy.

ABSTRACT: The design of bright short-wave infrared fluorophores remains a grand challenge. Here we investigate the impact of deuteration on the properties in a series of heptamethine dyes, the absorption of which spans near-infrared and SWIR regions. We demonstrate that it is a generally applicable strategy that leads to enhanced quantum yields of fluorescence, longer-lived singlet excited states and suppressed rates of non-radiative deactivation processes.

SUBMITTER: Janekova H 

PROVIDER: S-EPMC10805072 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature