Sequestration of Ruthenium Residues via Efficient Fluorous-enyne Termination.

ABSTRACT: The creation of polymers without metal contamination remains a significant challenge for metathesis-based polymerization techniques and has complicated applications in biomedical and electronic applications. This communication reports a new approach for the removal of ruthenium byproducts through the design of an enyne terminator for metathesis polymerization that contains a fluorous tag. Upon reaction of a living polymer chain with the enyne, the ruthenium center is captured as a stable sulfur-chelated complex that can be efficiently removed after a single filtration through a fluorous cartridge. Levels of ruthenium residues as determined by ICP-MS were found to depend on the monomer structure, eluting solvent, and the degree of polymerization targeted. Ruthenium residues were minimized t

SUBMITTER: Sui X 

PROVIDER: S-EPMC10805442 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature