Abnormal white matter structural network topological property in patients with temporal lobe epilepsy.

ABSTRACT:

Background

Diffusion tensor imaging (DTI) studies have demonstrated white matter (WM) abnormalities in patients with temporal lobe epilepsy (TLE). However, alterations in the topological properties of the WM structural network in patients with TLE remain unclear. Graph theoretical analysis provides a new perspective for evaluating the connectivity of WM structural networks.

Methods

DTI was used to map the structural networks of 18 patients with TLE (10 males and 8 females) and 29 (17 males and 12 females) age- and gender-matched normal controls (NC). Graph theory was used to analyze the whole-brain networks and their topological properties between the two groups. Finally, partial correlation analyses were performed on the weighted network properties and clinical characterist

SUBMITTER: Ai H 

PROVIDER: S-EPMC10805448 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature