In vitro study: methylene blue-based antibacterial photodynamic inactivation of Pseudomonas aeruginosa.

ABSTRACT: Pseudomonas aeruginosa is one of the most antibiotic-resistant and opportunistic pathogens in immunocompromised and debilitated patients. It is considered the cause of most severe skin infections and is frequently found in hospital burn units. Due to its high antibiotic resistance, eliminating P. aeruginosa from skin infections is quite challenging. Therefore, this study aims to assess the novel in vitro antibacterial activity of methylene blue using a 635-nm diode laser to determine the effective power and energy densities for inhibition of P. aeruginosa. The strain was treated with various concentrations of methylene blue and 635-nm diode laser at powers of 300 mW/cm² and 250 mW/cm². The diode laser's potency in the photo-destruction of methylene blue and its degrad

SUBMITTER: Zada L 

PROVIDER: S-EPMC10806092 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature