Trends of gastric cancer burdens attributable to risk factors in China from 2000 to 2050.

ABSTRACT:

Background

The incidence of gastric cancer (GC) decreased in past decades, which was thought largely attributable to risk factors control, yet China still accounts for 44% of global GC burdens. We aimed to estimate changing trajectories of proportions of GC burdens attributable to modifiable risk factors from 2000 to 2050 in China, to inform future targeted preventive strategies.

Methods

The incidence and new cases of GC were predicted to 2050 using Bayesian age-period-cohort model based on incidence data by anatomical subsites drawn from 682 cancer registries from National Central Cancer Registry. Population attributable fractions (PAFs) were calculated based on prevalence of risk factors and relative risks with GC. Temporal trends of PAFs were described by sex and categori

SUBMITTER: He F 

PROVIDER: S-EPMC10806286 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature