Potential contributions of the intrinsic retinal oscillations recording using non-invasive electroretinogram to bioelectronics.

ABSTRACT: Targeted electric signal use for disease diagnostics and treatment is emerging as a healthcare game-changer. Besides arrhythmias, treatment-resistant epilepsy and chronic pain, blindness, and perhaps soon vision loss, could be among the pathologies that benefit from bioelectronic medicine. The electroretinogram (ERG) technique has long demonstrated its role in diagnosing eye diseases and early stages of neurodegenerative diseases. Conspicuously, ERG applications are all based on light-induced responses. However, spontaneous, intrinsic activity also originates in retinal cells. It is a hallmark of degenerated retinas and its alterations accompany obesity and diabetes. To the extent that variables extracted from the resting activity of the retina measured by ERG allow the predictive diagnosi

SUBMITTER: Rodriguez-Arzate CA 

PROVIDER: S-EPMC10806452 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature