Cost-effectiveness of stepwise provisional versus systematic dual stenting strategies in patients with distal bifurcation left main stem lesions: economic analysis of the EBC MAIN trial.

ABSTRACT:

Background

In patients with distal bifurcation left main stem lesions requiring intervention, the European Bifurcation Club Left Main Coronary Stent Study trial found a non-significant difference in major adverse cardiac events (MACEs, composite of all-cause death, non-fatal myocardial infarction and target lesion revascularisation) favouring the stepwise provisional strategy, compared with the systematic dual stenting.

Aims

To estimate the 1-year cost-effectiveness of stepwise provisional versus systematic dual stenting strategies.

Methods

Costs in France and the UK, and MACE were calculated in both groups to estimate the incremental cost-effectiveness ratio (ICER). Uncertainty was explored by probabilistic bootstrapping. The analysis was conducted from the perspecti

SUBMITTER: Le Bras A 

PROVIDER: S-EPMC10806460 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature