Association between the triglyceride glucose index and low skeletal muscle mass: a cross-sectional study.

ABSTRACT:

Objectives

Triglyceride glucose (TyG) represents a consistent surrogate biomarker and index of insulin resistance (IR), IR has also been linked to skeletal muscle mass loss (SMM-L). Here, we evaluated the association between SMM-L and the TyG index (TyGi).

Design

An analytical cross-sectional study.

Setting

Tertiary care hospitals.

Participants

36 275 participants who underwent health checks between 1 January 2013 and 31 December 2020.

Primary and secondary outcome measures

A bioelectrical impedance analysis was used to assess the body composition, SMM-L was defined as low ASMI (total limb lean mass/height²) and TyGi was calculated as ln(triglycerides (mg/dL)×fasting blood glucose (mg/dL)/2).

Results

A total of 36 275 subjects were incl

SUBMITTER: Li Z 

PROVIDER: S-EPMC10806592 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature