Role of vitamin D supplementation in modifying outcomes after surgery: a systematic review of randomised controlled trials.

ABSTRACT:

Background

There is increasing evidence to suggest vitamin D plays a role in immune and vascular function; hence, it may be of biological and clinical relevance for patients undergoing major surgery. With a greater number of randomised studies being conducted evaluating the impact of vitamin D supplementation on surgical patients, it is an opportune time to conduct further analysis of the impact of vitamin D on surgical outcomes.

Methods

MEDLINE, EMBASE and the Cochrane Trials Register were interrogated up to December 2023 to identify randomised controlled trials of vitamin D supplementation in surgery. The risk of bias in the included studies was assessed using the Cochrane Risk of Bias tool. A narrative synthesis was conducted for all studies. The primary outcome assessed

SUBMITTER: Patel A 

PROVIDER: S-EPMC10806719 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature