Efficacy in bowel movement and change of gut microbiota on adult functional constipation patients treated with probiotics-containing products: a systematic review and meta-analysis.

ABSTRACT:

Objectives

This study aimed to pool the efficacy in bowel movement and explore the change of gut microbiota on adult functional constipated patients after probiotics-containing products treatment.

Design

Systematic review and meta-analysis.

Data sources

PubMed, Cochrane Library for published studies and ClinicalTrials.gov for 'grey' researches were independently investigated for randomised controlled trials up to November 2022.

Eligibility criteria, data extraction and synthesis

The intervention was probiotics-containing product, either probiotics or synbiotics, while the control was placebo. The risk of bias was conducted. The efficacy in bowel movement was indicated by stool frequency, stool consistency and Patient Assessment of Constipation Symptom (PAC-SYM)

SUBMITTER: Ding F 

PROVIDER: S-EPMC10806726 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature