Building a vertically integrated genomic learning health system: The biobank at the Colorado Center for Personalized Medicine.

ABSTRACT: Precision medicine initiatives across the globe have led to a revolution of repositories linking large-scale genomic data with electronic health records, enabling genomic analyses across the entire phenome. Many of these initiatives focus solely on research insights, leading to limited direct benefit to patients. We describe the biobank at the Colorado Center for Personalized Medicine (CCPM Biobank) that was jointly developed by the University of Colorado Anschutz Medical Campus and UCHealth to serve as a unique, dual-purpose research and clinical resource accelerating personalized medicine. This living resource currently has more than 200,000 participants with ongoing recruitment. We highlight the clinical, laboratory, regulatory, and HIPAA-compliant informatics infrastructure along with

SUBMITTER: Wiley LK 

PROVIDER: S-EPMC10806731 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature