Clinical outcomes and predictors of bleomycin polidocanol foam sclerotherapy treatment response in venous malformations.

ABSTRACT:

Objective

To evaluate the safety and efficacy of bleomycin polidocanol foam (BPF) sclerotherapy for venous malformations (VMs) and analyze the associated clinical outcomes and predictors.

Methods

We retrospectively assessed BPF sclerotherapy outcomes in 138 patients with VMs. We analyzed pain levels, lesion volume reduction, and subjective perception of response. Logistic regression analysis was performed to identify potential predictors of treatment outcome. Additionally, we carefully monitored and recorded complications.

Results

There was a notable average reduction in lesion volume by 78.50% ± 15.71%. The pain numerical rating scale (NRS) score decreased from 4.17 ± 2.63 prior to treatment to 1.05 ± 1.54 afterward, and 70.3% of the patients experienced effective re

SUBMITTER: Ni B 

PROVIDER: S-EPMC10807324 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature