Update of the risk assessment of polybrominated diphenyl ethers (PBDEs) in food.

ABSTRACT: The European Commission asked EFSA to update its 2011 risk assessment on polybrominated diphenyl ethers (PBDEs) in food, focusing on 10 congeners: BDE-28, -47, -49, -99, -100, -138, -153, -154, -183 and ‑209. The CONTAM Panel concluded that the neurodevelopmental effects on behaviour and reproductive/developmental effects are the critical effects in rodent studies. For four congeners (BDE-47, -99, -153, -209) the Panel derived Reference Points, i.e. benchmark doses and corresponding lower 95% confidence limits (BMDLs), for endpoint-specific benchmark responses. Since repeated exposure to PBDEs results in accumulation of these chemicals in the body, the Panel estimated the body burden at the BM

SUBMITTER: EFSA Panel on Contaminants in the Food Chain (CONTAM) 

PROVIDER: S-EPMC10807361 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature