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Multifactorial resistance of Bacillus subtilis spores to low-pressure plasma sterilization.


ABSTRACT: Common sterilization techniques for labile and sensitive materials have far-reaching applications in medical, pharmaceutical, and industrial fields. Heat inactivation, chemical treatment, and radiation are established methods to inactivate microorganisms, but pose a threat to humans and the environment and can damage susceptible materials or products. Recent studies have demonstrated that cold low-pressure plasma (LPP) treatment is an efficient alternative to common sterilization methods, as LPP's levels of radicals, ions, (V)UV-radiation, and exposure to an electromagnetic field can be modulated using different process gases, such as oxygen, nitrogen, argon, or synthetic (ambient) air. To further investigate the effects of LPP, spores of the Gram-positive model organism Bacillus subtil

SUBMITTER: Muratov E 

PROVIDER: S-EPMC10807416 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature