A highly diversified NLR cluster in melon contains homologs that confer powdery mildew and aphid resistance.

ABSTRACT: Podosphaera xanthii is the main causal agent of powdery mildew (PM) on Cucurbitaceae. In Cucumis melo, the Pm-w resistance gene, which confers resistance to P. xanthii, is located on chromosome 5 in a cluster of nucleotide-binding leucine-rich repeat receptors (NLRs). We used positional cloning and transgenesis, to isolate the Pm-w^{WMR 29} gene encoding a coiled-coil NLR (CC-NLR). Pm-w^{WMR 29} conferred high level of resistance to race 1 of PM and intermediate level of resistance to race 3 of PM. Pm-w^{WMR 29} turned out to be a homolog of the Aphis gossypii resistance gene Vat-1^{PI 161375}. We confirmed that Pm-w^{WMR 29} did not confer resistance to aphids, while

SUBMITTER: Boissot N 

PROVIDER: S-EPMC10807702 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature