Who are optimal candidates for primary tumor resection in patients with metastatic gastric adenocarcinoma? A population-based study.

ABSTRACT:

Background

The research aimed to construct a novel predictive nomogram to identify specific metastatic gastric adenocarcinoma (mGAC) populations who could benefit from primary tumor resection (PTR).

Method

Patients with mGAC were included in the SEER database and divided into PTR and non-PTR groups. The Kaplan-Meier analysis, propensity score matching (PSM), least absolute shrink and selection operator (LASSO) regression, multivariable logistic regression, and multivariate Cox regression methods were then used. Finally, the prediction nomograms were built and tested.

Results

3185 patients with mGAC were enrolled. Among the patients, 679 cases underwent PTR while the other 2506 patients didn't receive PTR. After PSM, the patients in the PTR group presented longer media

SUBMITTER: Song X 

PROVIDER: S-EPMC10807831 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature