Combined model integrating deep learning, radiomics, and clinical data to classify lung nodules at chest CT.

ABSTRACT:

Objectives

The study aimed to develop a combined model that integrates deep learning (DL), radiomics, and clinical data to classify lung nodules into benign or malignant categories, and to further classify lung nodules into different pathological subtypes and Lung Imaging Reporting and Data System (Lung-RADS) scores.

Materials and methods

The proposed model was trained, validated, and tested using three datasets: one public dataset, the Lung Nodule Analysis 2016 (LUNA16) Grand challenge dataset (n = 1004), and two private datasets, the Lung Nodule Received Operation (LNOP) dataset (n = 1027) and the Lung Nodule in Health Examination (LNHE) dataset (n = 1525). The proposed model used a stacked ensemble model by employing a machine learning (ML) approach with an AutoGluon-Tabu

SUBMITTER: Lin CY 

PROVIDER: S-EPMC10808169 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature