The tongue microbiome of young patients with chronic kidney disease and their healthy mothers.

ABSTRACT:

Objectives

Oral microbiome plays a crucial role in the incidence and development of oral diseases. An altered intestinal microbiome has been reported in adults with chronic kidney disease (CKD). This study aimed to characterize the tongue microbiome of young patients with CKD compared to their healthy mothers to identify the influence of CKD-associated factors on resilient tongue ecosystem.

Material and methods

Thirty patients with CKD (mean age, 14.2 years; 16 males and 14 females) and generalized gingivitis were included in the study. Swabs of the posterior tongue were collected from the patients and 21 mothers (mean age 40.8 years). Next-generation sequencing of 16S rDNA genes was employed to quantitatively characterize microbial communities.

Results

The bacterial

SUBMITTER: Hoefer KC 

PROVIDER: S-EPMC10808353 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature