Feasibility and outcome of third-generation transcatheter aortic valve implantation in patients with extra-large aortic annulus.

ABSTRACT:

Background

Many patients in need for transcatheter aortic valve implantation (TAVI) present with an aortic annulus size larger than recommended by the manufacturer's instructions for use (IFU).

Aims

To investigate procedural and short-term safety and efficacy of TAVI in patients with extra-large annuli (ELA).

Methods

30-day clinical outcome and valve performance as defined by VARC 3 of 144 patients with an aortic annulus size exceeding the permitted range were compared to a propensity-score matched control cohort of patients with an aortic annulus size consistent with the IFU.

Results

Area and perimeter was 730.4 ± 53.9 mm² and 96.7 ± 6.5 mm in the ELA group. Technical (96.5% vs. 94.4%) and device success (82.3% vs. 84.5%) were comparable in patients

SUBMITTER: Hof A 

PROVIDER: S-EPMC10808444 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature