Survival benefit of living donor kidney transplantation in patients on hemodialysis.

ABSTRACT:

Background

Donors bravely donate their kidneys because they expect that living donor kidney transplantation (LKT) confers benefits to recipients. However, the magnitude of the survival benefit of LKT is uncertain.

Methods

This prospective cohort study used two Japanese nationwide databases for dialysis and kidney transplantation and included 862 LKT recipients and 285,242 hemodialysis (HD) patients in the main model and 5299 LKT recipients and 151,074 HD patients in the supplementary model. We employed time-dependent model in the main model and assessed the hazard ratio and the difference in the restricted mean survival time (RMST) between LKT recipients and HD patients. In the main analysis of the main model (LKT, N = 675; HD, N = 675), we matched LKT recipients with HD pat

SUBMITTER: Goto S 

PROVIDER: S-EPMC10808530 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature