Retrospective cohort study to evaluate the continuous use of anticholesterolemics and diuretics in patients with COVID-19.

ABSTRACT:

Purpose

The purpose of this study is to evaluate the interference of the continuous use of drug classes in the expression of biomarkers during the first week of hospitalization and in the prognosis of patients with COVID-19.

Methods

The patients diagnosed with COVID-19 and confirmed with SARS-CoV-2 by RT-qPCR assay underwent the collection of fasting whole blood samples for further analysis. Other data also extracted for this study included age, sex, clinical symptoms, related comorbidities, smoking status, and classes of continuous use. Routine serum biochemical parameters, including alanine aminotransferase, aspartate aminotransferase, lactate dehydrogenase, C-reactive protein, N-terminal fragment of B-type natriuretic peptide, and cardiac troponin, were measured.

Resul

SUBMITTER: Oliveira FMS 

PROVIDER: S-EPMC10808793 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature