A computational model-based study on the feasibility of predicting post-splenectomy thrombosis using hemodynamic metrics.

ABSTRACT: For portal hypertensive patients with splenomegaly and hypersplenism, splenectomy is an effective surgery to relieve the complications. However, patients who have undergone splenectomy often suffer from portal venous system thrombosis, a sequela that requires prophylaxis and timely treatment to avoid deterioration and death. The aim of this study is to investigate the feasibility of predicting post-splenectomy thrombosis using hemodynamic metrics based on computational models. First, 15 portal hypertensive patients who had undergone splenectomy were enrolled, and their preoperative clinical data and postoperative follow-up results were collected. Next, computational models of the portal venous system were constructed based on the preoperative computed tomography angiography images and ultr

SUBMITTER: Wang T 

PROVIDER: S-EPMC10808826 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature