Evaluation of putative signatures of consciousness using specific definitions of responsiveness, connectedness, and consciousness.

ABSTRACT:

Background

Understanding the neural correlates of consciousness has important ramifications for the theoretical understanding of consciousness and for clinical anaesthesia. A major limitation of prior studies is the use of responsiveness as an index of consciousness. We identified a collection of measures derived from unresponsive subjects and more specifically their association with consciousness (any subjective experience) or connectedness (specific experience of environmental stimuli).

Methods

Using published data generated through the UNderstanding Consciousness Connectedness and Intra-Operative Unresponsiveness Study (NCT03284307), we evaluated 10 previously published resting-state EEG-based measures that were derived using unresponsiveness as a proxy for unconsciousnes

SUBMITTER: Casey CP 

PROVIDER: S-EPMC10808836 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature