Fracture Risk Among Living Kidney Donors 25 Years After Donation.

ABSTRACT:

Importance

Living kidney donors may have an increased risk of fractures due to reductions in kidney mass, lower concentrations of serum 1,25-dihydroxyvitamin D, and secondary increases in serum parathyroid hormone.

Objective

To compare the overall and site-specific risk of fractures among living kidney donors with strictly matched controls from the general population who would have been eligible to donate a kidney but did not do so.

Design, setting, and participants

This survey study was conducted between December 1, 2021, and July 31, 2023. A total of 5065 living kidney donors from 3 large transplant centers in Minnesota were invited to complete a survey about their bone health and history of fractures, and 16 156 population-based nondonor controls without a history

SUBMITTER: Maradit Kremers H 

PROVIDER: S-EPMC10809017 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature