Five-year changes in weight and risk of atrial fibrillation in the Danish Diet, Cancer, and Health Cohort.

ABSTRACT:

Aims

Obesity is a major risk factor for atrial fibrillation (AF). Compared with stable weight, gaining weight was associated with a higher risk of incident AF in observational studies. The results, however, are conflicting regarding weight loss and risk of AF. This study aimed to assess the association between 5-year weight changes and risk of incident AF.

Methods and results

The study was based on participants from the Danish Diet, Cancer, and Health Cohort. Body mass index (BMI) was assessed at a baseline examination and at a second examination 5 years later. Diagnoses of AF and co-morbidities were retrieved from the Danish National Patient Registry. In total, 43 758 participants without prior AF were included. The median age was 61 years and 54% were female. During a medi

SUBMITTER: Frederiksen TC 

PROVIDER: S-EPMC10809168 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature