Glycated serum proteins and albumin but not glycated albumin show negative correlation with BMI in an overweight/obese, diabetic population from the United States.

ABSTRACT:

Background and aims

Multiple previously published studies have shown a weak to medium, negative correlation between BMI and glycated albumin (GA). However, many of these studies were in populations with a narrow range of BMI. It is unknown whether this trend exists if a wider BMI range is used. This is an important question for proper interpretation of GA levels in obese populations.

Materials and methods

A retrospective analysis of clinical trial data (NCT02519309) was performed. After appropriate exclusions, 334 subjects remained. These included 73.7% with type 2 diabetes (T2D) diagnosis and 26.3% with prediabetes. BMI ranged from 24.8-86.9 kg/m². Laboratory data were measured in a CLIA-certified laboratory using commercially available, automated methods.

Res

SUBMITTER: Powers Carson J 

PROVIDER: S-EPMC10809425 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature