Retinal capillary perfusion heterogeneity in diabetic retinopathy detected by optical coherence tomography angiography.

ABSTRACT:

Background

Diabetic retinopathy (DR) is a leading cause of blindness and involves retinal capillary damage, microaneurysms, and altered blood flow regulation. Optical coherence tomography angiography (OCTA) is a non-invasive way of visualizing retinal vasculature but has not been used extensively to study blood flow heterogeneity. The purpose of this study is to detect and quantify blood flow heterogeneity utilizing en-face swept source OCTA in patients with DR.

Methods

This is a prospective clinical study which examined patients with either type 1 or 2 diabetes mellitus. Each included eye was graded clinically as no DR, mild DR, or moderate-severe DR. Ten consecutive en face 6 × 6 mm foveal SS-OCTA images were obtained from each eye using a PLEX Elite 9000 (Zeiss Meditec, D

SUBMITTER: Yuan PHS 

PROVIDER: S-EPMC10809479 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature