Ionizing radiation responses appear incidental to desiccation responses in the bdelloid rotifer Adineta vaga.

ABSTRACT:

Background

The remarkable resistance to ionizing radiation found in anhydrobiotic organisms, such as some bacteria, tardigrades, and bdelloid rotifers has been hypothesized to be incidental to their desiccation resistance. Both stresses produce reactive oxygen species and cause damage to DNA and other macromolecules. However, this hypothesis has only been investigated in a few species.

Results

In this study, we analyzed the transcriptomic response of the bdelloid rotifer Adineta vaga to desiccation and to low- (X-rays) and high- (Fe) LET radiation to highlight the molecular and genetic mechanisms triggered by both stresses. We identified numerous genes encoding antioxidants, but also chaperones, that are constitutively highly expressed, which may contribute to the protection

SUBMITTER: Moris VC 

PROVIDER: S-EPMC10809525 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature