Prognostic impact of oral microbiome on survival of malignancies: a systematic review and meta-analysis.

ABSTRACT:

Background

Recent studies have shown that there exists a significant correlation between oral microbiome and the occurrence of malignancies. However, the prognostic significance of oral microbiome for cancer patients remains unclear. The purpose of this meta-analysis is to evaluate the impact of oral microbiome on the survival of patients with malignant neoplasms.

Methods

We conducted a thorough literature search of PubMed, Embase, and Cochrane Library databases until September 2022. The hazard ratio (HR) with a corresponding 95% confidence interval (CI) was analyzed using Review Manager 5.4 software for survival outcomes, including overall survival (OS), disease-specific survival (DSS), progression-free survival (PFS), and disease-free survival (DFS).

Results

A total

SUBMITTER: Li S 

PROVIDER: S-EPMC10809532 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature