Differentiated genomic footprints suggest isolation and long-distance migration of Hmong-Mien populations.

ABSTRACT:

Background

The underrepresentation of Hmong-Mien (HM) people in Asian genomic studies has hindered our comprehensive understanding of the full landscape of their evolutionary history and complex trait architecture. South China is a multi-ethnic region and indigenously settled by ethnolinguistically diverse HM, Austroasiatic (AA), Tai-Kadai (TK), Austronesian (AN), and Sino-Tibetan (ST) people, which is regarded as East Asia's initial cradle of biodiversity. However, previous fragmented genetic studies have only presented a fraction of the landscape of genetic diversity in this region, especially the lack of haplotype-based genomic resources. The deep characterization of demographic history and natural-selection-relevant genetic architecture of HM people was necessary.

Results

SUBMITTER: He G 

PROVIDER: S-EPMC10809681 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature