Rapid turnover and short-term blooms of Escherichia coli in the human gut.

ABSTRACT: Escherichia coli (E. coli) is a common microorganism that is widely present in the environment and closely related to human health. The extent of E. coli presence in the human gut has been a subject of ongoing debate. Through whole-genome shotgun metagenomic sequencing, our study revealed that E. coli exists in the human body at a low abundance (average abundance 1.21%), with occasional short-term bursts leading to temporary increases in abundance, with the highest recorded at 50.91%. Further investigations into the factors contributing to these short-term blooms of E. coli showed significant variations in strain types and genomes within fecal samples collected from the same individuals at different time points. Evolutionary tree analysis indicated that samples

SUBMITTER: Han N 

PROVIDER: S-EPMC10810211 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature