Lymph node examination and survival in resected pancreatic ductal adenocarcinoma: retrospective study.

ABSTRACT:

Background

The minimum number of examined lymph nodes (ELN) required for adequate staging and best prediction of survival has not been established in pancreatic ductal adenocarcinoma (PDAC). The aim of the study was to investigate the influence of ELN on staging and survival in PDAC.

Methods

Patients undergoing partial or total pancreatectomy for PDAC at two European university hospitals between 2007 and 2018 were retrospectively reviewed. Multivariate Cox regression model and survival analyses were performed to verify adequate staging.

Results

Overall 341 (73 per cent) patients showed lymph node metastasis (N1/N2), whereas 125 (27 per cent) patients had no lymph node involvement (N0). With increasing number of ELN, the proportion of positive lymph nodes increased. Th

SUBMITTER: Goess R 

PROVIDER: S-EPMC10810280 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature