Remote Measurements of Tear Electrolyte Concentrations on Both Sides of an Inserted Contact Lens.

ABSTRACT: In this paper, a method is described to perform ion concentration measurements on both sides of an inserted contact lens, without physical contact with the eye or the contact lens. The outer surface of an eye is covered with a tear film that has multiple layers. The central aqueous layer contains electrolytes and proteins. When a contact lens is inserted, it becomes localized in the central layer, which creates two layers known as the pre-lens tear film (PLTF) and the post-lens tear film (PoLTF). The PoLTF is in direct contact with the sensitive corneal epithelial cells which control electrolyte concentrations in tears. It is difficult to measure the overall electrolyte concentration in tears because of the small 7 μL volume of bulk tears. No methods are known, and no method has been propo

SUBMITTER: Lakowicz JR 

PROVIDER: S-EPMC10810336 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature