Herpes zoster diagnosis and treatment in relation to incident dementia: A population-based retrospective matched cohort study.

ABSTRACT:

Background

Evidence suggests that some infectious diseases, such as herpes zoster (HZ), are associated with elevated risk of subsequent dementia, while certain anti-viral medications are associated with lower risk. We sought to evaluate associations between HZ diagnosis and treatment with incident dementia in a large, retrospective matched cohort.

Methods

Using ICD-9 and ICD-10 diagnosis codes in electronic medical records, we identified members of Kaiser Permanente Northwest age 50 and older from 2000-2019 with a HZ diagnosis during this period. A comparison group without HZ diagnosis was individually matched 3:1 on age at HZ diagnosis date (index date), sex, and membership length prior to index date. We excluded subjects with dementia diagnosed before the index date. Antih

SUBMITTER: Weinmann S 

PROVIDER: S-EPMC10810473 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature