West Nile virus spread in Europe: Phylogeographic pattern analysis and key drivers.

ABSTRACT:

Background

West Nile virus (WNV) outbreaks in birds, humans, and livestock have occurred in multiple areas in Europe and have had a significant impact on animal and human health. The patterns of emergence and spread of WNV in Europe are very different from those in the US and understanding these are important for guiding preparedness activities.

Methods

We mapped the evolution and spread history of WNV in Europe by incorporating viral genome sequences and epidemiological data into phylodynamic models. Spatially explicit phylogeographic models were developed to explore the possible contribution of different drivers to viral dispersal direction and velocity. A "skygrid-GLM" approach was used to identify how changes in environments would predict viral genetic diversity variatio

SUBMITTER: Lu L 

PROVIDER: S-EPMC10810478 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature