A reservoir of timescales emerges in recurrent circuits with heterogeneous neural assemblies.

ABSTRACT: The temporal activity of many physical and biological systems, from complex networks to neural circuits, exhibits fluctuations simultaneously varying over a large range of timescales. Long-tailed distributions of intrinsic timescales have been observed across neurons simultaneously recorded within the same cortical circuit. The mechanisms leading to this striking temporal heterogeneity are yet unknown. Here, we show that neural circuits, endowed with heterogeneous neural assemblies of different sizes, naturally generate multiple timescales of activity spanning several orders of magnitude. We develop an analytical theory using rate networks, supported by simulations of spiking networks with cell-type specific connectivity, to explain how neural timescales depend on assembly size and show th

SUBMITTER: Stern M 

PROVIDER: S-EPMC10810607 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature